4-Bromobenzyl bromide → HCID 12019294, compound

HRID 1250448Notes

Reaction equation

HRID 1250448 reaction equation
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:12])[C:3]=1[C:13]([O:15][CH3:16])=[O:14].[Br:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22]Br)=[CH:20][CH:19]=1>>[Br:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22][NH:1][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=[C:4]([CH3:12])[C:3]=2[C:13]([O:15][CH3:16])=[O:14])=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 685274-Bromobenzyl bromideHCID 12595022HCID 12595022, compound

Product 1

HCID 12019294HCID 12019294, compound

Procedure

Methyl 4-(4-bromobenzylamino)-2-methylquinoline-3-carboxylate was synthesized by the same method as described for 1-(4-(4-bromobenzylamino-2-methylquinolin-3-yl)ethanone (Example 1, Intermediate 2c), starting from methyl 4-amino-2-methylquinoline-3-carboxylate and 4-bromobenzyl bromide. Melting point: 89° C.; MS(ES+): 385/387.

Sources & evidence

ORD record
ord-8ea91c19ffd74f7a9b5cbbc019b02944
Source dataset
uspto-grants-2002_01
Patent number
US06339077B1

Reaction notes

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