HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobenzyl bromide → Methyl 6-bromo-4-benzylamino-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobenzyl bromide | HCID 68527 | — |
| Reactant | 1-(4-(4-Bromobenzylamino)-2-methylquinolin-3-yl)ethanone | HCID 11462804 | — |
| Reactant | Methyl 6-bromo4-amino-2-methylquinoline-3-carboxylate | HCID 18326326 | — |
| Product | Methyl 6-bromo-4-benzylamino-2-methylquinoline-3-carboxylate | HCID 12019297 | — |
Reaction Steps
Methyl 6-bromo-4-benzylamino-2-methylquinoline-3-carboxylate was synthesized by the same process as described for 1-(4-(4-bromobenzylamino)-2-methylquinolin-3-yl)ethanone (Example 1, Intermediate 2c) starting from methyl 6-bromo4-amino-2-methylquinoline-3-carboxylate and 4-bromobenzyl bromide. Melting point: 89° C.; MS(ES+): 385/387.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06339077B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-eb90666f4dee437cb58ffb4b3a62d4ee |
| Source note | uspto-grants-2002_01 |