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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1250454Generated: October 27, 2026

4-Bromobenzyl bromide → Methyl 4-(4-bromobenzylamino)-2-ethylquinoline-3-carboxylate

https://huagongshe.com/reaction/1250454

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromobenzyl bromideHCID 68527—
Reactant1-(4-(4-Bromobenzylamino)-2-methylquinolin-3-yl)ethanoneHCID 11462804—
ReactantMethyl 4-amino-2-ethylquinoline-3-carboxylateHCID 18326313—
ProductMethyl 4-(4-bromobenzylamino)-2-ethylquinoline-3-carboxylateHCID 12019312—

Reaction Steps

Methyl 4-(4-bromobenzylamino)-2-ethylquinoline-3-carboxylate was synthesized by the same process as described for 1-(4-(4-bromobenzylamino)-2-methylquinolin-3-yl)ethanone (Example 1, Intermediate 2c) starting from methyl 4-amino-2-ethylquinoline-3-carboxylate and 4-bromobenzyl bromide. MS(ES+): 399/401.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06339077B1
Source datasetuspto-grants-2002_01
ORD IDord-a3ecd71edf424508b77b67935c8cbf2a
Source noteuspto-grants-2002_01