HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Amino-2-methylquinolin-3-yl)ethanone → 1-(4-(4-Bromo-2-fluorobenzylamino)-2-methylquinolin-3-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Amino-2-methylquinolin-3-yl)ethanone | HCID 672297 | — |
| Reactant | 4-Bromo-2-fluorobenzyl bromide | HCID 2733660 | — |
| Reactant | 1-(4-(4-Bromobenzylamino)-2-methylquinolin-3-yl)ethanone | HCID 11462804 | — |
| Product | 1-(4-(4-Bromo-2-fluorobenzylamino)-2-methylquinolin-3-yl)ethanone | HCID 12019320 | — |
Reaction Steps
1-(4-(4-Bromo-2-fluorobenzylamino)-2-methylquinolin-3-yl)ethanone was synthesized by the same process as described for 1-(4-(4-bromobenzylamino)-2-methylquinolin-3-yl)ethanone (Example 1, Intermediate 2c) starting from 1-(4-amino-2-methylquinolin-3-yl)ethanone and 4-bromo-2-fluorobenzyl bromide. MS(ES+): 387/389.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06339077B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-5c8d499d989147fb977ef4e55e3c2aa2 |
| Source note | uspto-grants-2002_01 |