HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Amino-2-methylquinolin-3-yl)ethanone → 1-(4-(4-Bromo-2-chlorobenzylamino)-2-methylquinolin-3-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Amino-2-methylquinolin-3-yl)ethanone | HCID 672297 | — |
| Reactant | 1-(4-(4-Bromobenzylamino)-2-methylquinolin-3-yl)ethanone | HCID 11462804 | — |
| Reactant | 4-Bromo-1-(bromomethyl)-2-chlorobenzene | HCID 21914486 | — |
| Product | 1-(4-(4-Bromo-2-chlorobenzylamino)-2-methylquinolin-3-yl)ethanone | HCID 12019323 | — |
Reaction Steps
1-(4-(4-Bromo-2-chlorobenzylamino)-2-methylquinolin-3-yl)ethanone was synthesized by the same process as described for 1-(4-(4-bromobenzylamino)-2-methylquinolin-3-yl)ethanone (Example 1, Intermediate 2c) starting from 1-(4-amino-2-methylquinolin-3-yl)ethanone and 4-bromo-2-chlorobenzyl bromide. MS(FAB+): 403/405.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06339077B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-46aa2d36690345fbbea91459c2449aaa |
| Source note | uspto-grants-2002_01 |