4-Chloroquinoline → HCID 18326779, compound

HRID 1250470Notes

Reaction equation

HRID 1250470 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH2:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][NH:13]1>>[ClH:1].[CH2:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][N:13]1[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 691404-ChloroquinolineHCID 422478Isoindoline

Product 1

HCID 18326779HCID 18326779, compound

Procedure

The title compound m.p. 264-267° C. and MS: m/e=247.3 (M+H+), was prepared from 4-chloroquinoline and 2,3-dihydro-1H-isoindole.

Sources & evidence

ORD record
ord-7cad1bd4baeb484891b1941f463b8030
Source dataset
uspto-grants-2002_01
Patent number
US06339093B1

Reaction notes

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