1,2,3,4-Tetrahydroisoquinoline → 4-(3,4-Dihydroisoquinolin-2(1H)-yl)quinolin-2-amine

HRID 1250471Notes

Reaction equation

HRID 1250471 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([NH2:12])[CH:3]=1.[CH2:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][NH:14]1>>[CH2:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][N:14]1[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([NH2:12])[CH:3]=1

Participants

3

Reactant 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 140674074-Chloroquinolin-2-amine

Product 1

HCID 183267594-(3,4-Dihydroisoquinolin-2(1H)-yl)quinolin-2-amine

Procedure

The title compound, MS: m/e=276.3 (M+H+), was prepared from 4-chloro-quinolin-2-ylamine and 1,2,3,4-tetrahydroisoquinoline.

Sources & evidence

ORD record
ord-aeb8bb6c3d804d8dbc0a518f91336930
Source dataset
uspto-grants-2002_01
Patent number
US06339093B1

Reaction notes

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