1,2,3,4-Tetrahydroisoquinoline → HCID 18326780, compound

HRID 1250475Notes

Reaction equation

HRID 1250475 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([F:12])[CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH2:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][NH:14]1>>[ClH:1].[CH2:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][N:14]1[C:2]1[C:11]2[C:6](=[C:7]([F:12])[CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 27365874-Chloro-8-fluoroquinoline

Product 1

HCID 18326780HCID 18326780, compound

Procedure

The title compound, MS: m/e=279.2 (M+H+), was prepared from 4-chloro-8-fluoroquinoline and 1,2,3,4-tetrahydroisoquinoline.

Sources & evidence

ORD record
ord-f41ead7c2a0d4d5dbfe432fc4c3f0a2d
Source dataset
uspto-grants-2002_01
Patent number
US06339093B1

Reaction notes

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