1,2,3,4-Tetrahydroisoquinoline → 4-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinolin-6-ol hydrochloride

HRID 1250476Notes

Reaction equation

HRID 1250476 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH2:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][NH:14]1>>[ClH:1].[CH2:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][N:14]1[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 184331324-Chloroquinolin-6-ol

Product 1

HCID 183267574-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinolin-6-ol hydrochloride

Procedure

The title compound, MS: m/e=277.2 (M+H+), was prepared 4-chloro-quinolin-6-ol and 1,2,3,4-tetrahydroisoquinoline.

Sources & evidence

ORD record
ord-1c4e8842ba834738a7ff7332c47ba177
Source dataset
uspto-grants-2002_01
Patent number
US06339093B1

Reaction notes

Loading…