Water → tert-Butyl 8-oxo-5-azaspiro(2.5)octane-5-carboxylate

HRID 125079Notes

Reaction equation

HRID 125079 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[C:26]([OH:27])([CH3:28])([CH3:29])[CH3:30].[Cl:16][CH2:17][CH2:18][S+:19]([CH3:20])[CH3:21].[Cl:23][CH2:24][Cl:25].[I-:15].[OH2:22]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[C:12]2([CH2:13]1)[CH2:17][CH2:18]2

Participants

7

Reactant 6

HCID 962WaterHCID 6344DichloromethaneHCID 6386tert-ButanolHCID 30165Iodide IonHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 3808023InChI=1/C4H10ClS/c1-6(2)4-3-5/h3-4H2,1-2H3/q+

Product 1

HCID 57889898tert-Butyl 8-oxo-5-azaspiro(2.5)octane-5-carboxylate

Sources & evidence

ORD record
ord-93994c81f6054fa59628fdb13d4b5705
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…