4-Mercaptophenol → HCID 131723098, compound

HRID 1250938Notes

Reaction equation

HRID 1250938 reaction equation
Br[CH:2]([C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10][CH:9]=1)[C:3]([O:5][CH2:6][CH3:7])=[O:4].[SH:18][C:19]1[CH:24]=[CH:23][C:22]([OH:25])=[CH:21][CH:20]=1>>[CH2:6]([O:5][C:3](=[O:4])[CH:2]([S:18][C:19]1[CH:24]=[CH:23][C:22]([OH:25])=[CH:21][CH:20]=1)[C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10][CH:9]=1)[CH3:7]

Participants

3

Reactant 2

HCID 2401474-MercaptophenolHCID 13438950Ethyl bromo(naphthalen-1-yl)acetate

Product 1

HCID 131723098HCID 131723098, compoundYield 63.3%

Procedure

Ethyl[(4-hydroxyphenyl)sulfanyl](1-napthyl)acetate was prepared according to the general method as outlined in Example 1 (Step 1). Starting from ethyl bromo(1-napthyl)acetate (11.0 g, 38 mmol) and 4-mercaptophenol (4.8 g, 38 mmol), 8.14 g of ethyl[(4-hydroxyphenyl)sulfanyl](1-napthyl)acetate was isolated. Yield (64%); amber oil; MS 337.1 (M−H)−

Workup

  1. customEthyl[(4-hydroxyphenyl)sulfanyl](1-napthyl)acetate was prepared

Sources & evidence

ORD record
ord-5efa094f32444769a3a5cdc92d4ee9e1
Source dataset
uspto-grants-2002_01
Patent number
US06340691B1

Reaction notes

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