Triethylamine → HCID 18325666, compound

Participants

Reaction Steps

To a stirred solution of 4,5-dichloroimidazole (3.44 g, 25.1 mmol) and triethylamine (14.0 mL, 10.16 g, 100.4 mmol) in THF (30 mL) was added dropwise Chloro(N,N-dimethylamino)methoxyphosphine (3.55 g, 25.1 mmol) in CH2Cl2 (10 mL) at room temperature. The mixture was stirred for 2 h at room temperature. The reaction mixture was filtered to remove the resulting salt, and the solvent was removed under reduced pressure to give the crude product as a yellow oil (2.81 g, 79%). 31P NMR (CDCl3) δ 129.3.

Provenance & Evidence