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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1251064Generated: November 2, 2026

Ethanol → Ethyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoate

https://huagongshe.com/reaction/1251064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant2-(4-Cyclopropanecarbonyl-phenyl)-2-methylpropionamideHCID 23499851—
ProductEthyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoateHCID 9813859—

Reaction Steps

Dissolve 2-(4-cyclopropanecarbonyl-phenyl)-2-methyl-propionamide (100 mg) in ethanol and bubble in hydrochloride gas for 5 minutes while stirring. Reflux for 10 hours, distill off the ethanol and extract into ethyl acetate. Evaporate the solvent in vacuo to give the title compound as an oil (50 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06340761B1
Source datasetuspto-grants-2002_01
ORD IDord-aefbd905c9aa451793c4b408427b6205
Source noteuspto-grants-2002_01