HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 22502442, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | Benzonitrile, 4-(trifluoromethyl)- | HCID 67995 | — |
| Reactant | HCID 22502967 | HCID 22502967 | — |
| Product | HCID 22502442 | HCID 22502442 | — |
Reaction Steps
6-Methoxy-3-(4-trifluoromethylphenyl)isoquinolin-1-one obtained by reacting N-methyl-4-methoxy-2-methylbenzamide (1.0 g) and 4-trifluoromethylbenzonitrile (0.96 g) according to Example 10-1 was reacted with phosphorus oxychloride (10 ml) according to Example 10-2, to give 1-chloro-6-methoxy-3-(4-trifluoromethylphenyl)isoquinoline dihydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06340759B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-f07aa17b9332425f8037fbfd8425efea |
| Source note | uspto-grants-2002_01 |