関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | (+)-Pulegone | HCID 442495 | — |
| 反応物 | Potassium tert-butoxide | HCID 23665647 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | Pulegol | HCID 92793 | 98% |
反応手順
A 200 ml capacity autoclave was charged with 30.4 g (200 mmol) of pulegone, 19.1 mg (0.02 mmol) of RuCl2(PPh3)3(propanediamine), 44.9 mg (0.4 mmol) of t-BuOK and 2-propanol (15 ml), and the mixture was stirred at 30° C. for 18 hours while forcing 3 Mpa of hydrogen. After completion of the reaction, hydrogen was purged and the reaction solution was concentrated and distilled under a reduced pressure to obtain 30.2 g of pulegol. The yield was 98%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06342644B1 |
|---|
| 出典データセット | uspto-grants-2002_01 |
|---|
| ORD ID | ord-35fda5d58b8c49709da5c0377dab6a76 |
|---|
| 出典メモ | uspto-grants-2002_01 |
|---|
