HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-[3,4-(Methylenedioxy)benzyl]-benzo[b]thiophene-3-sulfonylchloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 2-[3,4-(Methylenedioxy)benzyl]benzo[b]thiophene | HCID 22998407 | — |
| Product | 2-[3,4-(Methylenedioxy)benzyl]-benzo[b]thiophene-3-sulfonylchloride | HCID 22998385 | — |
Reaction Steps
2-[3,4-(methylenedioxy)benzyl]benzo[b]thiophene-3-sulfonyl chloride was prepared by the method of Example 40B using DMF (9.1 mmoles, 0.70 ml), sulfuryl chloride (7.7 mmoles, 0.62 ml) and 2-[3,4-(methylenedioxy)benzyl]benzo[b]thiophene (4.6 mmoles, 1.2 g). Flash chromatography (5% ethyl acetate/hexanes) provided 0.71 g (42%) of a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06342610B2 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-e0462239cee54073b12e565de5db69a3 |
| Source note | uspto-grants-2002_01 |