HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfur Dioxide → HCID 18324212, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfur Dioxide | HCID 1119 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1-Methylindole | HCID 11781 | — |
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Product | HCID 18324212 | HCID 18324212 | — |
Reaction Steps
2-Methylindole-2-sulfonyl chloride was prepared by the method of Example 34 with 1-methylindole (7.8 mmols, 1.0 ml), t-BuLi (1.7 m, 9.4 mmols, 5.5 ml), sulfur dioxide, NCS (8.6 mmols, 1.2 g) and THF (15 ml). Flash chromatography (2% ethyl acetate/hexanes) provided 0.66 g (36%) of a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06342610B2 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-645074c2c7c949aebc82ddbb86c156ab |
| Source note | uspto-grants-2002_01 |