3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]aniline → 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(1-phenyl-3-(1-(trifluoromethyl)cyclopropyl)-1H-pyrazol-5-yl)urea
Reaction equation
[CH3:29][O:30][c:31]1[cH:32][c:33]2[c:34]([O:43][c:44]3[cH:45][c:46]([NH2:47])[cH:48][cH:49][cH:50]3)[n:35][cH:36][n:37][c:38]2[cH:39][c:40]1[O:41][CH3:42].[c:1]1(-[n:7]2[n:8][c:9]([C:22]3([C:25]([F:26])([F:27])[F:28])[CH2:23][CH2:24]3)[cH:10][c:11]2[NH:12][C:13]([O:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)=[O:21])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[n:7]2[n:8][c:9]([C:22]3([C:25]([F:26])([F:27])[F:28])[CH2:23][CH2:24]3)[cH:10][c:11]2[NH:12][C:13](=[O:21])[NH:47][c:46]2[cH:45][c:44]([O:43][c:34]3[c:33]4[cH:32][c:31]([O:30][CH3:29])[c:40]([O:41][CH3:42])[cH:39][c:38]4[n:37][cH:36][n:35]3)[cH:50][cH:49][cH:48]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-ade01498773d4dd3a6f7ef42e3d0f0b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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