HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22998418, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | MLS002608206 | HCID 237069 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22998418 | HCID 22998418 | — |
Reaction Steps
2-(4-dimethylaminobenzyl)benzo[b]thiophene was prepared by the method of Example 47B with α-(2-benzo[b]thienyl)-4-dimethylaminobenzyl alcohol (7.5 mmoles, 2.1 g), triethylsilane (2.8 mmoles, 1.3 ml), CH2Cl2 (50 ml) and TFA (11.2 mmoles, 0.9 ml). Flash chromatography (10% ethyl acetate/hexanes) provided 1.5 g (73%—for two steps) of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06342610B2 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-c2f8f52d367943a5a99e2bfb2f68e452 |
| Source note | uspto-grants-2002_01 |