1-(Chloromethoxy)-2-methoxyethane → HCID 69983700, compound

HRID 1251788Notes

Reaction equation

HRID 1251788 reaction equation
[CH3:1][C:2]1[C:6]([CH3:7])=[C:5]([NH:8][S:9]([C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)(=[O:11])=[O:10])[O:4][N:3]=1.[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22]Cl>>[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22][N:8]([C:5]1[O:4][N:3]=[C:2]([CH3:1])[C:6]=1[CH3:7])[S:9]([C:12]1[S:13][CH:14]=[CH:15][CH:16]=1)(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 22998429HCID 22998429, compound

Product 1

HCID 69983700HCID 69983700, compoundYield 34%

Procedure

N-(methyoxyethoxymethyl)-N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide was prepared in the same manner as described in Example 32B using N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide and methoxyethoxymethyl chloride resulting in 34% yield. HPLC analysis of the crude oil obtained after workup showed that the oil was approximately 96% pure and so was used in the next step without further purification.

Workup

  1. customHPLC analysis of the crude oil obtained after workup
  2. customso was used in the next step without further purification

Sources & evidence

ORD record
ord-bdcca7fd14a84c0c9576fb5ffb03f43e
Source dataset
uspto-grants-2002_01
Patent number
US06342610B2

Reaction notes

Loading…