Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Trifluoromethyl)phenylboronic acid → N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| 반응물 | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| 생성물 | N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole | HCID 22998451 | 75% |
반응 단계
N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole was prepared in the same manner as described in Example 32C using 4-trifluoromethylbenzene boronic acid and N-(5-bromothiophene sulfonyl)pyrrole. Purification by column chromatography using 2% ethyl acetate/hexanes gave the pure sulfonamide as a white powder in 75% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06342610B2 |
| 출처 데이터셋 | uspto-grants-2002_01 |
| ORD ID | ord-577802ef309f440c8cc7449f44a03f0f |
| 출처 메모 | uspto-grants-2002_01 |