Sodium borohydride → 2-(Imidazol-1-yl)-1-(thiazol-2-yl)ethanol

HRID 1251896Notes

Reaction equation

HRID 1251896 reaction equation
[N:1]1([CH2:6][C:7]([C:9]2[S:10][CH:11]=[CH:12][N:13]=2)=[O:8])[CH:5]=[CH:4][N:3]=[CH:2]1.[BH4-].[Na+]>CO>[N:1]1([CH2:6][CH:7]([C:9]2[S:10][CH:11]=[CH:12][N:13]=2)[OH:8])[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 223249842-(Imidazol-1-yl)-1-(thiazol-2-yl)-ethanone

Product 1

HCID 223250302-(Imidazol-1-yl)-1-(thiazol-2-yl)ethanolYield 60%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-(Imidazol-1-yl)-1-(thiazol-2-yl)ethanone was reduced with sodium borohydride in methanol to give 2-(imidazol-1-yl)-1-(thiazol-2-yl)ethanol in 60% yield.

Sources & evidence

ORD record
ord-5100b9eb78d7477e9c400649ccaa3c35
Source dataset
uspto-grants-2002_01
Patent number
US06342765B1

Reaction notes

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