HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-[1-(4-fluorophenyl)-2-(2-methylimidazol-1-yl)ethoxy]-2-(4-fluorophenethyl)benzoate → Methyl 5-[2-(imidazol-1-yl)-1-(thiazol-2-yl)ethoxy]-2-(4-fluorophenethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-[1-(4-fluorophenyl)-2-(2-methylimidazol-1-yl)ethoxy]-2-(4-fluorophenethyl)benzoate | HCID 18324372 | — |
| Reactant | Methyl 2-(4-fluorophenethyl)-5-hydroxybenzoate | HCID 18324453 | — |
| Reactant | 2-(Imidazol-1-yl)-1-(thiazol-2-yl)ethanol | HCID 22325030 | — |
| Product | Methyl 5-[2-(imidazol-1-yl)-1-(thiazol-2-yl)ethoxy]-2-(4-fluorophenethyl)benzoate | HCID 18324507 | — |
Reaction Steps
Methyl 5-[2-(imidazol-1-yl)-1-(thiazol-2-yl)ethoxy]-2-(4-fluorophenethyl)benzoate was prepared from 2-(imidazol-1-yl)-1-(thiazol-2-yl)ethanol and methyl 2-(4-fluorophenethyl)-5-hydroxybenzoate by the Mitsunobu methodology used for the preparation of methyl 5-[2-(2-methylimidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenethyl)benzoate in Example 45.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06342765B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-fb69508a69d949d1ad240f3bfe25a0c3 |
| Source note | uspto-grants-2002_01 |