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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1251905Generated: November 3, 2026

Hydroxide → 4-[2-(Imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl) benzoic acid

https://huagongshe.com/reaction/1251905

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxideHCID 961—
ReactantMethyl 4-[2-(imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl)benzoateHCID 18324444—
SolventMethanolHCID 887—
Product4-[2-(Imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl) benzoic acidHCID 53916630—

Reaction Steps

4-[2-(imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl) benzoic acid was prepared from methyl 4-[2-(imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl)benzoate by treatment with aqueous hydroxide in methanol and used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06342765B1
Source datasetuspto-grants-2002_01
ORD IDord-7dea7ac90af34a5797c93fe450543583
Source noteuspto-grants-2002_01