Acetone → HCID 13881179, compound

HRID 1251942Notes

Reaction equation

HRID 1251942 reaction equation
[CH:1]([C:4]1([CH3:18])[N:8]2[C:9](=[O:16])[C:10]3[C:11](=[N:12][CH:13]=[CH:14][CH:15]=3)[C:7]2=[N:6][C:5]1=[O:17])([CH3:3])[CH3:2].CC(C)=[O:21]>O>[OH:21][C:7]12[NH:6][C:5](=[O:17])[C:4]([CH:1]([CH3:3])[CH3:2])([CH3:18])[N:8]1[C:9](=[O:16])[C:10]1[C:11]2=[N:12][CH:13]=[CH:14][CH:15]=1

Participants

4

Reactant 2

HCID 180AcetoneHCID 13246864HCID 13246864, compound

Product 1

HCID 13881179HCID 13881179, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2 g of 3-isopropyl-3-methyl-2H-imidazo[1',2':1,2]pyrrolo[3,4-b]pyridine-2,5(3H)-dione in 90 ml of acetone and 10 ml of water is stirred at room temperature for about 16 hours. The solution is subsequently evaporated to dryness and the residue is crystallized from ethyl acetate/n-hexane. There is obtained 1,9b-dihydro-9b-hydroxy-3-isopropyl-3-methyl-2H-imidazo[1',2':1,2]pyrrolo[3,4-b]pyridine-2,5(3H)-dione as colorless crystals, m.p. 151°-153° C.

Workup

  1. customThe solution is subsequently evaporated to dryness
  2. customthe residue is crystallized from ethyl acetate/n-hexane

Sources & evidence

ORD record
ord-aabda16fafa749f9b6aa2b2e40348b09
Source dataset
uspto-grants-1988_05
Patent number
US04741767

Reaction notes

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