Acetyl chloride → 2-Acetoxymethyl-6-chloroaniline

HRID 1252004Notes

Reaction equation

HRID 1252004 reaction equation
[NH2:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].[C:11](Cl)(=[O:13])[CH3:12]>>[C:11]([O:5][CH2:4][C:3]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:10])[C:2]=1[NH2:1])(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 14155407(2-Amino-3-chlorophenyl)methanol

Product 1

HCID 141554092-Acetoxymethyl-6-chloroaniline

Procedure

This material was prepared from 2-amino-3-chlorobenzyl alcohol and acetyl chloride by the general procedure outlined in Example 82. The product was isolated as an amber oil and was characterized by IR and 'H NMR spectroscopy and combustion analysis.

Workup

  1. customThe product was isolated as an amber oil

Sources & evidence

ORD record
ord-b86e2342ca1e44c787caab69ad22950e
Source dataset
uspto-grants-1988_05
Patent number
US04741764

Reaction notes

Loading…