1,3-Difluoro-2-nitrobenzene → 2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

HRID 1252011Notes

Reaction equation

HRID 1252011 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N+:9]([O-:11])=[O:10].[Cl:12][C:13]1[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[CH:15][C:14]=1[OH:23]>>[Cl:12][C:13]1[CH:18]=[C:17]([C:19]([F:20])([F:21])[F:22])[CH:16]=[CH:15][C:14]=1[O:23][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 879221,3-Difluoro-2-nitrobenzeneHCID 27366032-Chloro-4-(trifluoromethyl)phenol

Product 1

HCID 541374142-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

Procedure

This material was prepared in 47% yeild from 2,6-difluoronitrobenzene and 2-chloro-4-trifluoromethylphenol following the general procedure outlined in Example 88. The product was isolated as an oil which was characterized by IR and 1H NMR spectroscopy.

Workup

  1. customThe product was isolated as an oil which

Sources & evidence

ORD record
ord-0bd36e1be26a4e3782e80ff456c046ec
Source dataset
uspto-grants-1988_05
Patent number
US04741764

Reaction notes

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