Toluene → HCID 2760819, compound

Participants

Reaction Conditions

Reaction Steps

Into a 3 liter reaction vessel equipped with stirrer, thermometer, reflux condenser and Dean Stark trap is placed 710.0 grams of 2-methyl-2,4-pentanediol; 372.0 grams of boric acid and 500 grams of toluene. With stirring the reaction mass is heated to 87° C. and, by way of the Dean Stark trap water is eliminated and the alcohol having the structure: ##STR77## is recovered. The reaction temperature gradually rises to 125° C. as water is eliminated and the total reaction time is 10 hours. The total amount of water evolved is 252.0 grams. When the water of reaction ceases to evolve, the reaction mass is cooled to 70° C. Once all of the water is removed the compound having the structure: ##STR78## as recovered weighs 1227.0 grams. This material having the structure: ##STR79## is used for Examples II, III, IV and V, infra.

Provenance & Evidence