Imidazole → N-(3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenoyl)-imidazole

HRID 1252045Notes

Reaction equation

[CH3:1][C:2]([CH2:7][CH2:8][CH:9]=[C:10]([CH3:22])[CH2:11][CH2:12][CH:13]=[C:14]([CH3:21])[CH2:15][CH2:16][CH:17]=[C:18]([CH3:20])[CH3:19])=[CH:3][C:4]([OH:6])=O.[NH:23]1[CH:27]=[CH:26][N:25]=[CH:24]1>>[CH3:1][C:2]([CH2:7][CH2:8][CH:9]=[C:10]([CH3:22])[CH2:11][CH2:12][CH:13]=[C:14]([CH3:21])[CH2:15][CH2:16][CH:17]=[C:18]([CH3:20])[CH3:19])=[CH:3][C:4]([N:23]1[CH:27]=[CH:26][N:25]=[CH:24]1)=[O:6]

Participants

Reactant 2

HCID 795Imidazole

HCID 1285703,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenic acid

Product 1

HCID 53858195N-(3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenoyl)-imidazoleYield 91.5%

Procedure

The same procedure as in Example 1 was repeated except that 6.1 g of 3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenoic acid and 1.4 g of imidazole were used as the starting materials. 6.5 g (91%) of the title compound was obtained as a colorless oil.

Sources & evidence

ORD record: ord-9f4a6c5994984e3fa3e4a8c2deffc12c
Source dataset: uspto-grants-1988_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04742058

Reaction notes

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