HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 14129783, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-[4-(5-Nitro-1H-indol-3-yl)piperidin-1-yl]ethan-1-one | HCID 14129782 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 14129783 | HCID 14129783 | 77.3% |
Reaction Steps
A mixture of 3-(1-acetyl-4-piperidyl)-5-nitroindole (4 g), 2N aqueous sodium hydroxide solution (100 ml) and ethanol (100 ml) was refluxed for 7 hours. The reaction mixture was cooled and the resulting precipitate was collected by filtration. This solid was recrystallized from ethanol-water to give 3-(4-piperidyl)-5-nitroindole (2.64 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04742057 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-7edfdf6defb947759fc102a9a205a17c |
| Source note | uspto-grants-1988_05 |