tert-Butanol → Tert-butyl 4-formylbenzoate

HRID 1252230Notes

Reaction equation

[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1)=[O:2].[C:12]([OH:16])([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:7](=[O:8])[C:6]1[CH:10]=[CH:11][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=1)([CH3:15])([CH3:14])[CH3:13]

Participants

Reactant 2

HCID 6386tert-Butanol

HCID 124246204-Formylbenzoyl chloride

Product 1

HCID 2751588Tert-butyl 4-formylbenzoate

Procedure

The starting 4-formylbenzoic acid t-butyl ester was prepared from 4-formylbenzoic acid chloride by esterification with t-butanol.

Sources & evidence

ORD record: ord-c50bdab9eaa84250aca3881a58fd0565
Source dataset: uspto-grants-1988_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04742052

Reaction notes

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