Ammonia → HCID 86742150, compound

HRID 1252247Notes

Reaction equation

HRID 1252247 reaction equation
[CH:1]([N:4]1[C:9]([CH3:10])=[CH:8][C:7](=[O:11])[CH2:6][S:5]1(=[O:13])=[O:12])([CH3:3])[CH3:2].[NH3:14]>CO>[NH2:14][C:9]([CH3:10])=[CH:8][C:7](=[O:11])[CH2:6][S:5]([NH:4][CH:1]([CH3:3])[CH3:2])(=[O:13])=[O:12]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 12470829HCID 12470829, compound

Product 1

HCID 86742150HCID 86742150, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A suspension of 10 g of 2-isopropyl-3-methyl-1,2-thiazin-5(6H)-one 1,1-dioxide in 100 ml of methanol was reacted with ammonia in accordance with the procedure described in Example 1. The solution obtained was concentrated to dryness under reduced pressure and the solid residue was recrystallized from isopropanol. There were obtained 10.1 g of 4-amino-N-isopropyl-2-oxo-3-pentenesulfonamide in the form of colorless crystals, m.p. 119°-121°.

Workup

  1. customThe solution obtained
  2. concentrationwas concentrated to dryness under reduced pressure
  3. customthe solid residue was recrystallized from isopropanol

Sources & evidence

ORD record
ord-688214776e734ae3815a1adc1b228ad0
Source dataset
uspto-grants-1988_05
Patent number
US04742069

Reaction notes

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