1,3-Cyclohexanedione → 2-[(Dimethylamino)methylidene]cyclohexane-1,3-dione

Participants

Reaction Steps

11.9 g (100 mM) of N.N-dimethylformamide dimethylacetal was dropwise added to 5.6 g (50 mM) of cyclohexane-1,3-dione being stirred in an ice bath. The mixture was subjected to a reaction at 25° C. for 7 hours. The low-boiling substances in the reaction mixture were distilled off. The residue was recrystallized from ethyl acetatehexane to obtain 7.7 g of a desired compound as a yellow crystal with an yield of 92%.

Provenance & Evidence