HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 13982441, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | benzhydryl (6R)-3-(chloromethyl)-7-[[(2Z)-2-methoxyimino-2-[2-(tritylamino)-1,3-thiazol-4-yl]acetyl]amino]-5,8-dioxo-5lambda4-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate | HCID 14070463 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 13982441 | HCID 13982441 | — |
Reaction Steps
The oily substance obtained in (A) was dissolved in 50 ml of acetone, and 670 mg (4.47 mmol) of sodium iodide was added. The mixture was stirred at room temperature for 30 minutes. The reaction solution was poured into ice water, and extracted with ethyl acetate. The extracted solution was washed with a 5% sodium thiosulfate aqueous solution, with water and with a saturated sodium chloride aqueous solution, then dried over anhydrous sodium sulfate and concentrated under reduced pressure, whereby an oily substance was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04742053 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-b1fb44a587c44f22bcf719635259241a |
| Source note | uspto-grants-1988_05 |