Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 14254943 | HCID 14254943 | — |
| Product | HCID 14254944 | HCID 14254944 | — |
Reaction Steps
Thionyl chloride (2.3 mL) was added dropwise to 110 mL methanol cooled to -10° C. Next 10.4 g 4-propylthio-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid was added in one portion. The solution was warmed to reflux for 6 hours, then cooled to -45° C., and the product precipitated in sufficiently pure form for the purposes of this invention; yield 8.45 g; m.p. 93°-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04743290 |
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| Source dataset | uspto-grants-1988_05 |
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| ORD ID | ord-ba49dcf48c1448b3a34653ae49230997 |
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| Source note | uspto-grants-1988_05 |
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