HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → Ethyl 4-methyl-2-(naphthalen-1-yl)-1H-imidazole-5-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 1-Naphthalenemethanamine | HCID 8355 | — |
| Reactant | Ethyl 2,3-dioxobutanoate | HCID 12260829 | — |
| Product | Ethyl 4-methyl-2-(naphthalen-1-yl)-1H-imidazole-5-carboxylate | HCID 53404405 | — |
Reaction Steps
A mixture of 9.1 g of 1-naphthalenemethylamine, 8.4 g of 2,3-dioxobutyric acid, ethyl ester, (Z)-2-oxime and 115 ml of acetonitrile was refluxed for 5 hours and then cooled. The solid was collected, giving 7.0 g of 5-methyl-2-(1-naphthalenyl)-1H-imidazole-4-carboxylic acid, ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04743586 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-67a6393867264316a505305509117e8d |
| Source note | uspto-grants-1988_05 |