Hydrazine → HCID 131715522, compound

HRID 1252375Notes

Reaction equation

HRID 1252375 reaction equation
[CH3:1][C:2]1[NH:6][C:5]([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][CH:8]=2)=[N:4][C:3]=1[C:14]([O:16]CC)=O.[NH2:19][NH2:20]>O>[CH3:1][C:2]1[NH:6][C:5]([C:7]2[CH:8]=[CH:9][C:10]([CH3:13])=[CH:11][CH:12]=2)=[N:4][C:3]=1[C:14]([NH:19][NH2:20])=[O:16]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 43445104ethyl 5-methyl-2-(4-methylphenyl)-1H-imidazole-4-carboxylate

Product 1

HCID 131715522HCID 131715522, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 4.9 g of the above ester and 15 ml of anhydrous hydrazine was stirred and refluxed overnight. Water was added, the mixture was evaporated and the residue recrystallized from ethanol, giving 3.45 g of 5-methyl-2-(4-methylphenyl)-1H-imidazole-4-carboxylic acid, hydrazide.

Workup

  1. temperaturerefluxed overnight
  2. customthe mixture was evaporated
  3. customthe residue recrystallized from ethanol

Sources & evidence

ORD record
ord-a7d0a76b6a9c4d0c8adca3b6796d835c
Source dataset
uspto-grants-1988_05
Patent number
US04743586

Reaction notes

Loading…