Benzyl 3-(ethoxycarbonyl)-2-(2-methylpropyl)propenoate → 3-(Ethoxycarbonyl)-2-(2-methylpropyl)propanoic acid

HRID 1252377노트

반응식

HRID 1252377 반응식
[CH2:1]([O:3][C:4]([CH:6]=[C:7]([CH2:18][CH:19]([CH3:21])[CH3:20])[C:8]([O:10]CC1C=CC=CC=1)=[O:9])=[O:5])[CH3:2]>C(O)C.[Pd]>[CH2:1]([O:3][C:4]([CH2:6][CH:7]([CH2:18][CH:19]([CH3:20])[CH3:21])[C:8]([OH:10])=[O:9])=[O:5])[CH3:2]

참가 물질

4

반응물 1

HCID 53921709Benzyl 3-(ethoxycarbonyl)-2-(2-methylpropyl)propenoate

생성물 1

HCID 143030363-(Ethoxycarbonyl)-2-(2-methylpropyl)propanoic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

E and Z benzyl 3-(ethoxycarbonyl)-2-(2-methylpropyl)propenoate (25.0 g., 0.09 mol.) was dissolved in ethanol and hydrogenated at 50° C. under 37.5 psi in the presence of 5% palladium on charcoal (2.5 g.). The resultant mixture was filtered through Celite and the solvent removed by evaporation in vacuo to yield 3-(ethoxycarbonyl)-2-(2-methylpropyl)propanoic acid as a mixture of isomers in the form of a thick oil.

후처리

  1. filtrationThe resultant mixture was filtered through Celite
  2. customthe solvent removed by evaporation in vacuo

출처 및 근거

ORD 기록
ord-b6a69208754e47a9b29e4a061f5636be
출처 데이터셋
uspto-grants-1988_05
특허 번호
US04743587

반응 노트

불러오는 중…