Oxalyl chloride → HCID 20139949, compound

Participants

Reaction Steps

A mixture of 2-(5-n-butylthiophen-2-yl)-cyclopropanecarboxylic acid (9.0 g, 0.04 mol) and oxalyl chloride (6.35 g, 0.05 mol) in hexane (70 ml) was stirred at room temperature for 2 hours and then warmed at 60° C. for 3 hours. The hexane and excess oxalyl chloride were removed in vacuo to give 2-(5-n-butylthiophen-2-yl)-cyclopropanecarbonyl chloride (9.7 g, 100%) as a pale yellow liquid which was used in the next stage without further purification.

Provenance & Evidence