HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium cyanate → HCID 20140046, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium cyanate | HCID 11378442 | — |
| Reactant | HCID 14276100 | HCID 14276100 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 20140046 | HCID 20140046 | 25.8% |
Reaction Steps
Potassium cyanate (8.63 g, 0.106 mole) was added to a solution of 6-aminoisoquinolin-5-one (5.0 g, 0.0213 mole) in hydrochloric acid (pH=1) while maintaining the acidity constant by subsequent addition of concentrated hydrochloric acid. After stirring for about 11/2 hours, the product precipitated andwas obtained by filtration. Recrystallization from 50% aqueous ethanol gave 1.03 g (25%) of the desired product, m.p. >310° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04743607 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-bde22ab086ee4371b47cc9b0fac561ce |
| Source note | uspto-grants-1988_05 |