Toluene → 1-Methoxy-2-[p-(p-n-octylphenyl)-benzoyloxy]-propane

HRID 1252654Notes

Reaction equation

HRID 1252654 reaction equation
[CH3:1][O:2][CH2:3][CH:4]([OH:6])[CH3:5].[CH2:7]([C:15]1[CH:20]=[CH:19][C:18]([C:21]2[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=2)=[CH:17][CH:16]=1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C1(C)C=CC=CC=1>N1C=CC=CC=1>[CH3:1][O:2][CH2:3][CH:4]([O:6][C:25](=[O:26])[C:24]1[CH:23]=[CH:22][C:21]([C:18]2[CH:19]=[CH:20][C:15]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])=[CH:16][CH:17]=2)=[CH:29][CH:28]=1)[CH3:5]

Participants

5

Reactant 3

HCID 1140TolueneHCID 79001-Methoxy-2-propanolHCID 147459674'-Octyl-4-biphenylcarboxylic acid chloride

Product 1

HCID 197424101-Methoxy-2-[p-(p-n-octylphenyl)-benzoyloxy]-propane

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.8 g of 1-methoxy-2-propanol, 3.2 g of p-(p-n-octylphenyl)-benzoic acid chloride 20 ml of toluene and 2.1 ml of pyridine are boiled under reflux for 6 hours. The pyridinium chloride is filtered off hot with suction and the filtrate is worked up in the customary manner. Optically active 1-methoxy-2-[p-(p-n-octylphenyl)-benzoyloxy]-propane is obtained

Workup

  1. temperatureunder reflux for 6 hours
  2. filtrationThe pyridinium chloride is filtered off hot with suction

Sources & evidence

ORD record
ord-2987767043e6476fbb4a4d55047830d3
Source dataset
uspto-grants-1988_05
Patent number
US04744918

Reaction notes

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