HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Chromanecarbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3,4-dihydro-2H-1-benzopyran-2-carboxylic acid | HCID 2723665 | — |
| Product | 2-Chromanecarbonyl chloride | HCID 2794583 | — |
Reaction Steps
A solution of 3,4-dihydro-1-benzopyran-2-carboxylic acid (0.59 g 3.3 mmol) in thionyl chloride (15 ml) was stirred at 20° C. for 16 hours. Excess thionyl chloride was evaporated, azeotroping with dry toluene, to give 3,4-dihydro-1-benzopyran-2-carboxylic acid chloride as a yellow oil (νmax (film) 1805 cm-1) which was used immediately.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04745114 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-73c2bee6628f480898c24ec8e6cef8d4 |
| Source note | uspto-grants-1988_05 |