Saccharin → Pseudosaccharin chloride

Participants

Reaction Steps

A mixture of saccharin (10 g; 0.055 mol) and phosphorus pentachloride (12.6 g; 0.061 mol) was kept at a bath temperature of 180° C. for 1.5 hours, followed by cooling. To the reaction mixture was added ether (50 ml), followed by vigorous stirring. Crystals were collected by filtration to give the objective compound (3.68 g). Yield, 33%. M.P., 144.5°-145.5° C.

Provenance & Evidence