Iodine → HCID 19781372, compound

Participants

Reaction Steps

In a 1-liter three-neck flask equipped with a stirrer, reflux condenser, dropping funnel, and thermometer were placed 23.3 g (1.00 mol) of magnesium powder, 82.6 g (0.640 mol) of methyltrichlorosilane, and 200 ml of diethyl ether. The magnesium was activated with iodine and dibromoethane. The flask was cooled to 10° C. to 0° C. A mixture of 50.0 g (0.319 mol) of p-methoxybenzyl chloride and 300 ml of diethyl ether was added dropwise with stirring from the dropping funnel over 4 hours at 10° C. to 0° C. After aging at room temperature for 1 hour, excess magnesium and magnesium chloride were removed by suction filtration. The filtrate was distilled to give 48.8 g (0.208 mol) of the desired product in a yield of 65%.

Provenance & Evidence