1-[2-benzoylthio-3-methoxybutanoyl]L-proline → 1-[2-mercapto-3-methoxybutanoyl]-L-proline

HRID 1252830Notes

Reaction equation

HRID 1252830 reaction equation
C([S:9][CH:10]([CH:21]([O:23][CH3:24])[CH3:22])[C:11]([N:13]1[CH2:20][CH2:19][CH2:18][C@H:14]1[C:15]([OH:17])=[O:16])=[O:12])(=O)C1C=CC=CC=1.C(SCC(CSC)C(N1CCC[C@H]1C(O)=O)=O)(=O)C>>[SH:9][CH:10]([CH:21]([O:23][CH3:24])[CH3:22])[C:11]([N:13]1[CH2:20][CH2:19][CH2:18][C@H:14]1[C:15]([OH:17])=[O:16])=[O:12]

Participants

3

Reactant 2

HCID 186324661-[2-benzoylthio-3-methoxybutanoyl]L-prolineHCID 539119981-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline

Product 1

HCID 536677191-[2-mercapto-3-methoxybutanoyl]-L-proline

Procedure

By substituting N-[2-benzoylthio-3-methoxybutanoyl]-L-proline for the N-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline in the procedure of Example 56, Step (c), N-[2-mercapto-3-methoxybutanoyl]-L-proline is obtained.

Sources & evidence

ORD record
ord-7f62f2f4c2614d21930ef529345925a0
Source dataset
uspto-grants-1988_05
Patent number
US04745124

Reaction notes

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