Sulfuric Acid → HCID 13823607, compound

Participants

Reaction Steps

5 g (0.013 mole) of N-[2-ethoxycarbonyl-2-acetylvinyl]-N'-(2,6-dichloro-4-trifluoromethyl-phenyl)-hydrazine are dissolved in 50 ml of ethanol, 1 ml of concentrated sulphuric acid is added and the mixture is heated for 1 hour under reflux. The reaction mixture is concentrated in vacuo, taken up in methylene chloride, washed with saturated sodium hydrogen carbonate solution, the methylene chloride phase is dried over magnesium sulphate and concentrated in vacuo. 4.1 g (86% of theory) of 4-ethoxycarbonyl-5-methyl-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-pyrazole with a melting point of 61°-62° C. are obtained.

Provenance & Evidence