HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium ethoxide → ethyl 2-chloro-5-{1,2,5,7-tetrahydro-2,4-dioxo-thieno[3,4-d]pyrimidin-3(4H)-yl}-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | Ethyl 2-chloro-5-{3-[4-(methoxycarbonyl)-2,5-dihydro-thien-3-yl]ureido}-benzoate | HCID 20130667 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl 2-chloro-5-{1,2,5,7-tetrahydro-2,4-dioxo-thieno[3,4-d]pyrimidin-3(4H)-yl}-benzoate | HCID 20130698 | — |
Reaction Steps
using ethyl 2-chloro-5-{3-[4-(methoxycarbonyl)-2,5-dihydro-thien-3-yl]ureido}-benzoate with sodium ethylate in ethanol there is obtained ethyl 2-chloro-5-{1,2,5,7-tetrahydro-2,4-dioxo-thieno[3,4-d]pyrimidin-3(4H)-yl}-benzoate, m.p. 194°-196° C.,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04746352 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-aa20c3408a704186886daafaf4887ce7 |
| Source note | uspto-grants-1988_05 |