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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1252915Generated: November 3, 2026

Dimethyl Sulfate → HCID 20130621, compound

https://huagongshe.com/reaction/1252915

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
ReactantHCID 20130640HCID 20130640—
SolventDimethylformamideHCID 6228—
ProductHCID 20130621HCID 20130621—

Reaction Steps

using isopropyl 2-chloro-4-fluoro-5-[3,6-dihydro-4-ethyl-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-benzoate and dimethyl sulphate in dimethylformamide there is obtained isopropyl 2-chloro-4-fluoro-5-[3,6-dihydro-4-ethyl-3,5-dimethyl-2,6-dioxo-1(2H)-pyrimidinyl]-benzoate, 1H-NMR (CDCl3, 400 MHz) 7.82 ppm (d, 1H), 7.33 ppm (d, 1H), 5.23 ppm (m, 1H), 3.51 ppm (s, 3H), 2.71 ppm (m, 2H), 2.04 ppm (s, 3H), 1.35 ppm (d, 6H), 1.28 ppm (t, 3H),

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04746352
Source datasetuspto-grants-1988_05
ORD IDord-655458ada7a14ba9844de0c3423959ee
Source noteuspto-grants-1988_05