HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester → Isopropyl 2-chloro-4-fluoro-5-{3-[4-(methoxycarbonyl)-2,5-dihydrothien-3-yl]ureido}-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester | HCID 98424 | — |
| Reactant | Isopropyl 2-chloro-4-fluoro-5-ureidobenzoate | HCID 20130672 | — |
| Product | Isopropyl 2-chloro-4-fluoro-5-{3-[4-(methoxycarbonyl)-2,5-dihydrothien-3-yl]ureido}-benzoate | HCID 20130628 | — |
Reaction Steps
using isopropyl 2-chloro-4-fluoro-5-ureidobenzoate and methyl 3-oxotetrahydrothiophene-4-carboxylate there is obtained isopropyl 2-chloro-4-fluoro-5-{3-[4-(methoxycarbonyl)-2,5-dihydro-thien-3-yl]ureido}-benzoate,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04746352 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-fca9b6939e644e799ccd9f61dca7ce7e |
| Source note | uspto-grants-1988_05 |