HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexadiene → 2,3-Dihydro-4,7-dimethoxy-1H-indene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexadiene | HCID 11605 | — |
| Reactant | 4,7-dimethoxy-2,3-dihydro-1H-inden-1-one | HCID 606012 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2,3-Dihydro-4,7-dimethoxy-1H-indene | HCID 12654133 | — |
Reaction Steps
A mixture of intermediate A (1 g, 6 mmole), 1,3-cyclohexadiene (0.6 ml, 6 mmole), and toluene (15 ml) was refluxed about 15 hours under a nitrogen atmosphere. The solvent was removed under reduced pressure to yield 1.5 g of crude Diels-Alder adduct (intermediate B), which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04746607 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-22717950577c41cf82522d615a371747 |
| Source note | uspto-grants-1988_05 |